Neutropenia (most common): In most cases interruption of therapy or reduction of the dose by 50% will result in increase in ANC in 3-7 days. If ANC <0.5x10⁹/L or if ANC does not increase after dose reduction, therapy should be discontinued until ANC >1x10⁹/L
Thrombocytopenia
Elevated liver function tests (AST, ALT, bilirubin)
Hazardous Drug (high level) Considered to be a potential teratogen and carcinogen in humans. Use chemotherapy precautions when handling or disposing
5 day per week dosing schedule allows patients to receive IV therapy as outpatients
Use valganciclovir orally as there is no oral formulation of ganciclovir. Note: valganciclovir can NOT be substituted for ganciclovir on a one-to-one basis