Pregnancy:
Breastfeeding:
Renal function, K, Mg, HCO3, liver enzymes, CBC.
Frequency depends on course, but daily reasonable during initiation.
Adequate hydration prior to infusion is recommended to reduce risk of nephrotoxicity.
Premedication with analgesics, antiemetics, antihistamines and hydrocortisone may be required for infusion related reactions.
If renal dysfunction is due to amphotericin, the daily total can be decreased by 50% or the dose can be given every other day.
Antimicrobial class: Antifungal - polyene