Streptococcus pyogenes, Group A

General Information

Gram positive cocci in chains, beta-hemolytic

Reservoir is human skin and oropharynx/mucous membranes.

Person-to-person transmission.

Occasionally foodborne.

Known to cause severe disease in pregnant women both antepartum, intrapartum and post partum 'puerperal sepsis'

Exhaustive and fascinating list.

Most common manifestations are:

  • Tonsillopharyngitis ("Strep throat")

  • Skin infections (impetigo, erysipelas, cellulitis)

Other invasive infections:

  • Bacteremia

  • Endocarditis

  • Necrotizing fasciitis

  • Meningitis

  • Toxic shock syndrome

  • Pneumonia

  • Other sterile space infections

Post-infectious immunologically mediated phenomena such as glomerulonephritis and rheumatic fever

Scarlet fever

Contact and droplet precautions for invasive disease for the first 24hrs of antimicrobial therapy or after last debridement, otherwise no precautions.

Post-exposure prophylaxis may be indicated. Invasive disease is a reportable condition