Guidelines
Late Onset Neonatal Sepsis

Late Onset Neonatal Sepsis

Laboratory

If suspected late onset neonatal sepsis (onset beyond 72 hours of life), perform:

  • CBC & differential
  • Blood culture ± urine/CSF culture

Is there severe clinical disease or suspected GI pathologies?

For example:

  • Hypotension
  • Poor perfusion
  • Necrotizing enteral colitis (NEC)
  • Spontaneous intestinal perforation

Notes

This guidelines outlines the approach to the management of late-onset sepsis in NICU patients; it is not intended as a substitute for clinical judgment

If any specific questions, please contact the Neonatologist